Effect of CHRFAM7A Δ2bp gene variant on secondary inflammation after spinal cord injury.

The α7 neuronal nicotinic acetylcholine receptors (α7nAChRs) are essential for anti-inflammatory responses. The human-specific CHRFAM7A gene and its 2bp deletion polymorphism (Δ2bp variant) encodes a structurally-deficient α7nAChRs that may impact the anti-inflammatory function. We studied 45 spinal...

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Autores principales: Mingkuan Lin, Wan Huang, Nadine Kabbani, Mark M Theiss, John F Hamilton, James M Ecklund, Yvette P Conley, Yoram Vodovotz, David Brienza, Amy K Wagner, Emily Robbins, Gwendolyn A Sowa, Robert H Lipsky
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/4a386b81cf444528804f9e1a7194413f
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