Antibody-guided design and identification of CD25-binding small antibody mimetics using mammalian cell surface display

Abstract Small antibody mimetics that contain high-affinity target-binding peptides can be lower cost alternatives to monoclonal antibodies (mAbs). We have recently developed a method to create small antibody mimetics called FLuctuation-regulated Affinity Proteins (FLAPs), which consist of a small p...

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Autores principales: Kyra See, Tetsuya Kadonosono, Kotaro Miyamoto, Takuya Tsubaki, Yumi Ota, Marina Katsumi, Sumoe Ryo, Kazuki Aida, Misa Minegishi, Tatsuhiro Isozaki, Takahiro Kuchimaru, Shinae Kizaka-Kondoh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4a3de7440c4544338c3384a1404a0c94
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