Antibody-guided design and identification of CD25-binding small antibody mimetics using mammalian cell surface display
Abstract Small antibody mimetics that contain high-affinity target-binding peptides can be lower cost alternatives to monoclonal antibodies (mAbs). We have recently developed a method to create small antibody mimetics called FLuctuation-regulated Affinity Proteins (FLAPs), which consist of a small p...
Guardado en:
Autores principales: | Kyra See, Tetsuya Kadonosono, Kotaro Miyamoto, Takuya Tsubaki, Yumi Ota, Marina Katsumi, Sumoe Ryo, Kazuki Aida, Misa Minegishi, Tatsuhiro Isozaki, Takahiro Kuchimaru, Shinae Kizaka-Kondoh |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/4a3de7440c4544338c3384a1404a0c94 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
A reliable murine model of bone metastasis by injecting cancer cells through caudal arteries
por: Takahiro Kuchimaru, et al.
Publicado: (2018) -
A fluorescent protein scaffold for presenting structurally constrained peptides provides an effective screening system to identify high affinity target-binding peptides.
por: Tetsuya Kadonosono, et al.
Publicado: (2014) -
A luciferin analogue generating near-infrared bioluminescence achieves highly sensitive deep-tissue imaging
por: Takahiro Kuchimaru, et al.
Publicado: (2016) -
Gastrobodies are engineered antibody mimetics resilient to pepsin and hydrochloric acid
por: Niels Wicke, et al.
Publicado: (2021) -
Bacterially derived synthetic mimetics of mammalian oligomannose prime antibody responses that neutralize HIV infectivity
por: Ralph Pantophlet, et al.
Publicado: (2017)