Cajal bodies are linked to genome conformation

Nuclear bodies can nucleate at sites of active transcription and are beneficial for efficient gene expression. Here, the authors show that Cajal bodies, a prominent type of nuclear body, contribute to genome organization with global effects on gene expression and RNA splicing fidelity.

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Autores principales: Qiuyan Wang, Iain A. Sawyer, Myong-Hee Sung, David Sturgill, Sergey P. Shevtsov, Gianluca Pegoraro, Ofir Hakim, Songjoon Baek, Gordon L. Hager, Miroslav Dundr
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Q
Acceso en línea:https://doaj.org/article/4a414664746b45f382dd862a8abf1053
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