Cajal bodies are linked to genome conformation
Nuclear bodies can nucleate at sites of active transcription and are beneficial for efficient gene expression. Here, the authors show that Cajal bodies, a prominent type of nuclear body, contribute to genome organization with global effects on gene expression and RNA splicing fidelity.
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Nature Portfolio
2016
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oai:doaj.org-article:4a414664746b45f382dd862a8abf10532021-12-02T17:32:08ZCajal bodies are linked to genome conformation10.1038/ncomms109662041-1723https://doaj.org/article/4a414664746b45f382dd862a8abf10532016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10966https://doaj.org/toc/2041-1723Nuclear bodies can nucleate at sites of active transcription and are beneficial for efficient gene expression. Here, the authors show that Cajal bodies, a prominent type of nuclear body, contribute to genome organization with global effects on gene expression and RNA splicing fidelity.Qiuyan WangIain A. SawyerMyong-Hee SungDavid SturgillSergey P. ShevtsovGianluca PegoraroOfir HakimSongjoon BaekGordon L. HagerMiroslav DundrNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-17 (2016) |
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Science Q Qiuyan Wang Iain A. Sawyer Myong-Hee Sung David Sturgill Sergey P. Shevtsov Gianluca Pegoraro Ofir Hakim Songjoon Baek Gordon L. Hager Miroslav Dundr Cajal bodies are linked to genome conformation |
description |
Nuclear bodies can nucleate at sites of active transcription and are beneficial for efficient gene expression. Here, the authors show that Cajal bodies, a prominent type of nuclear body, contribute to genome organization with global effects on gene expression and RNA splicing fidelity. |
format |
article |
author |
Qiuyan Wang Iain A. Sawyer Myong-Hee Sung David Sturgill Sergey P. Shevtsov Gianluca Pegoraro Ofir Hakim Songjoon Baek Gordon L. Hager Miroslav Dundr |
author_facet |
Qiuyan Wang Iain A. Sawyer Myong-Hee Sung David Sturgill Sergey P. Shevtsov Gianluca Pegoraro Ofir Hakim Songjoon Baek Gordon L. Hager Miroslav Dundr |
author_sort |
Qiuyan Wang |
title |
Cajal bodies are linked to genome conformation |
title_short |
Cajal bodies are linked to genome conformation |
title_full |
Cajal bodies are linked to genome conformation |
title_fullStr |
Cajal bodies are linked to genome conformation |
title_full_unstemmed |
Cajal bodies are linked to genome conformation |
title_sort |
cajal bodies are linked to genome conformation |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/4a414664746b45f382dd862a8abf1053 |
work_keys_str_mv |
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