Cajal bodies are linked to genome conformation

Nuclear bodies can nucleate at sites of active transcription and are beneficial for efficient gene expression. Here, the authors show that Cajal bodies, a prominent type of nuclear body, contribute to genome organization with global effects on gene expression and RNA splicing fidelity.

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Autores principales: Qiuyan Wang, Iain A. Sawyer, Myong-Hee Sung, David Sturgill, Sergey P. Shevtsov, Gianluca Pegoraro, Ofir Hakim, Songjoon Baek, Gordon L. Hager, Miroslav Dundr
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/4a414664746b45f382dd862a8abf1053
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spelling oai:doaj.org-article:4a414664746b45f382dd862a8abf10532021-12-02T17:32:08ZCajal bodies are linked to genome conformation10.1038/ncomms109662041-1723https://doaj.org/article/4a414664746b45f382dd862a8abf10532016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms10966https://doaj.org/toc/2041-1723Nuclear bodies can nucleate at sites of active transcription and are beneficial for efficient gene expression. Here, the authors show that Cajal bodies, a prominent type of nuclear body, contribute to genome organization with global effects on gene expression and RNA splicing fidelity.Qiuyan WangIain A. SawyerMyong-Hee SungDavid SturgillSergey P. ShevtsovGianluca PegoraroOfir HakimSongjoon BaekGordon L. HagerMiroslav DundrNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qiuyan Wang
Iain A. Sawyer
Myong-Hee Sung
David Sturgill
Sergey P. Shevtsov
Gianluca Pegoraro
Ofir Hakim
Songjoon Baek
Gordon L. Hager
Miroslav Dundr
Cajal bodies are linked to genome conformation
description Nuclear bodies can nucleate at sites of active transcription and are beneficial for efficient gene expression. Here, the authors show that Cajal bodies, a prominent type of nuclear body, contribute to genome organization with global effects on gene expression and RNA splicing fidelity.
format article
author Qiuyan Wang
Iain A. Sawyer
Myong-Hee Sung
David Sturgill
Sergey P. Shevtsov
Gianluca Pegoraro
Ofir Hakim
Songjoon Baek
Gordon L. Hager
Miroslav Dundr
author_facet Qiuyan Wang
Iain A. Sawyer
Myong-Hee Sung
David Sturgill
Sergey P. Shevtsov
Gianluca Pegoraro
Ofir Hakim
Songjoon Baek
Gordon L. Hager
Miroslav Dundr
author_sort Qiuyan Wang
title Cajal bodies are linked to genome conformation
title_short Cajal bodies are linked to genome conformation
title_full Cajal bodies are linked to genome conformation
title_fullStr Cajal bodies are linked to genome conformation
title_full_unstemmed Cajal bodies are linked to genome conformation
title_sort cajal bodies are linked to genome conformation
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/4a414664746b45f382dd862a8abf1053
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