Baicalin Enhanced Oral Bioavailability of Sorafenib in Rats by Inducing Intestine Absorption

Background: Sorafenib (SOR) is an oral, potent, selective, irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) used as the first-line therapy for advanced hepatocellular carcinoma (HCC). Baicalin (BG) is used as adjuvant therapy for hepatitis, which accounts for the le...

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Autores principales: Jingyao Wei, Ruijuan Liu, Jiali Zhang, Shuaibing Liu, Dan Yan, Xueqian Wen, Xin Tian
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/4a48cab5eb4c44fbbdb5dd4acb8b1158
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