Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages

The development of malaria parasites is controlled by coordinated changes in gene expression. Here, the authors show that the three-dimensional genome structure of human malaria parasites is strongly connected with transcriptional activity of specific gene families throughout the life cycles of Plas...

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Autores principales:	Evelien M. Bunnik, Kate B. Cook, Nelle Varoquaux, Gayani Batugedara, Jacques Prudhomme, Anthony Cort, Lirong Shi, Chiara Andolina, Leila S. Ross, Declan Brady, David A. Fidock, Francois Nosten, Rita Tewari, Photini Sinnis, Ferhat Ay, Jean-Philippe Vert, William Stafford Noble, Karine G. Le Roch
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4a6a36d14fb4490e84769dc9194c6458
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spelling	oai:doaj.org-article:4a6a36d14fb4490e84769dc9194c64582021-12-02T17:33:04ZChanges in genome organization of parasite-specific gene families during the Plasmodium transmission stages10.1038/s41467-018-04295-52041-1723https://doaj.org/article/4a6a36d14fb4490e84769dc9194c64582018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04295-5https://doaj.org/toc/2041-1723The development of malaria parasites is controlled by coordinated changes in gene expression. Here, the authors show that the three-dimensional genome structure of human malaria parasites is strongly connected with transcriptional activity of specific gene families throughout the life cycles of Plasmodium falciparum and Plasmodium vivax parasites.Evelien M. BunnikKate B. CookNelle VaroquauxGayani BatugedaraJacques PrudhommeAnthony CortLirong ShiChiara AndolinaLeila S. RossDeclan BradyDavid A. FidockFrancois NostenRita TewariPhotini SinnisFerhat AyJean-Philippe VertWilliam Stafford NobleKarine G. Le RochNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Evelien M. Bunnik Kate B. Cook Nelle Varoquaux Gayani Batugedara Jacques Prudhomme Anthony Cort Lirong Shi Chiara Andolina Leila S. Ross Declan Brady David A. Fidock Francois Nosten Rita Tewari Photini Sinnis Ferhat Ay Jean-Philippe Vert William Stafford Noble Karine G. Le Roch Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages
description	The development of malaria parasites is controlled by coordinated changes in gene expression. Here, the authors show that the three-dimensional genome structure of human malaria parasites is strongly connected with transcriptional activity of specific gene families throughout the life cycles of Plasmodium falciparum and Plasmodium vivax parasites.
format	article
author	Evelien M. Bunnik Kate B. Cook Nelle Varoquaux Gayani Batugedara Jacques Prudhomme Anthony Cort Lirong Shi Chiara Andolina Leila S. Ross Declan Brady David A. Fidock Francois Nosten Rita Tewari Photini Sinnis Ferhat Ay Jean-Philippe Vert William Stafford Noble Karine G. Le Roch
author_facet	Evelien M. Bunnik Kate B. Cook Nelle Varoquaux Gayani Batugedara Jacques Prudhomme Anthony Cort Lirong Shi Chiara Andolina Leila S. Ross Declan Brady David A. Fidock Francois Nosten Rita Tewari Photini Sinnis Ferhat Ay Jean-Philippe Vert William Stafford Noble Karine G. Le Roch
author_sort	Evelien M. Bunnik
title	Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages
title_short	Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages
title_full	Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages
title_fullStr	Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages
title_full_unstemmed	Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages
title_sort	changes in genome organization of parasite-specific gene families during the plasmodium transmission stages
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/4a6a36d14fb4490e84769dc9194c6458
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Changes in genome organization of parasite-specific gene families during the Plasmodium transmission stages

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