Loop competition and extrusion model predicts CTCF interaction specificity

Boundaries of topologically associated domains in genomes are marked by CTCF and cohesin binding. Here the authors predict CTCF interaction specificity by building a simple mathematical model with features including loop competition and extrusion.

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Autores principales: Wang Xi, Michael A. Beer
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4a7e3fcaccb741f6871932d44d8598bb
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