Loop competition and extrusion model predicts CTCF interaction specificity

Boundaries of topologically associated domains in genomes are marked by CTCF and cohesin binding. Here the authors predict CTCF interaction specificity by building a simple mathematical model with features including loop competition and extrusion.

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Detalles Bibliográficos
Autores principales:	Wang Xi, Michael A. Beer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4a7e3fcaccb741f6871932d44d8598bb
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spelling	oai:doaj.org-article:4a7e3fcaccb741f6871932d44d8598bb2021-12-02T14:21:21ZLoop competition and extrusion model predicts CTCF interaction specificity10.1038/s41467-021-21368-02041-1723https://doaj.org/article/4a7e3fcaccb741f6871932d44d8598bb2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21368-0https://doaj.org/toc/2041-1723Boundaries of topologically associated domains in genomes are marked by CTCF and cohesin binding. Here the authors predict CTCF interaction specificity by building a simple mathematical model with features including loop competition and extrusion.Wang XiMichael A. BeerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Wang Xi Michael A. Beer Loop competition and extrusion model predicts CTCF interaction specificity
description	Boundaries of topologically associated domains in genomes are marked by CTCF and cohesin binding. Here the authors predict CTCF interaction specificity by building a simple mathematical model with features including loop competition and extrusion.
format	article
author	Wang Xi Michael A. Beer
author_facet	Wang Xi Michael A. Beer
author_sort	Wang Xi
title	Loop competition and extrusion model predicts CTCF interaction specificity
title_short	Loop competition and extrusion model predicts CTCF interaction specificity
title_full	Loop competition and extrusion model predicts CTCF interaction specificity
title_fullStr	Loop competition and extrusion model predicts CTCF interaction specificity
title_full_unstemmed	Loop competition and extrusion model predicts CTCF interaction specificity
title_sort	loop competition and extrusion model predicts ctcf interaction specificity
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/4a7e3fcaccb741f6871932d44d8598bb
work_keys_str_mv	AT wangxi loopcompetitionandextrusionmodelpredictsctcfinteractionspecificity AT michaelabeer loopcompetitionandextrusionmodelpredictsctcfinteractionspecificity
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Loop competition and extrusion model predicts CTCF interaction specificity

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