Recombinant attenuated Salmonella Typhimurium with heterologous expression of the Salmonella Choleraesuis O-polysaccharide: high immunogenicity and protection

Abstract Non-typhoidal Salmonella are associated with gastrointestinal disease worldwide and invasive disease in Africa. We constructed novel bivalent vaccines through the recombinant expression of heterologous O-antigens from Salmonella Choleraesuis in Salmonella Typhimurium. A recombinant Asd+ pla...

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Autores principales: Xinxin Zhao, Qinlong Dai, Dekang Zhu, Mafeng Liu, Shun Chen, Kunfeng Sun, Qiao Yang, Ying Wu, Qingke Kong, Renyong Jia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/4a9286ab7c4242bcbaefd653df4dc7a2
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