Transcriptional and Post-Transcriptional Polar Effects in Bacterial Gene Deletion Libraries

Single-gene deletion libraries have allowed genome-wide characterization of gene function and interactions. While each mutant intends to disrupt the function of a single gene, it can unintentionally target other genes, such as those located in the same operon as the deletion.

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Autores principales: André Mateus, Malay Shah, Johannes Hevler, Nils Kurzawa, Jacob Bobonis, Athanasios Typas, Mikhail M. Savitski
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/4ab3295f19b5446c8fc949767b9b3412
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