Transcriptional and Post-Transcriptional Polar Effects in Bacterial Gene Deletion Libraries
Single-gene deletion libraries have allowed genome-wide characterization of gene function and interactions. While each mutant intends to disrupt the function of a single gene, it can unintentionally target other genes, such as those located in the same operon as the deletion.
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Main Authors: | , , , , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2021
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Subjects: | |
Online Access: | https://doaj.org/article/4ab3295f19b5446c8fc949767b9b3412 |
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