Transcriptional and Post-Transcriptional Polar Effects in Bacterial Gene Deletion Libraries
Single-gene deletion libraries have allowed genome-wide characterization of gene function and interactions. While each mutant intends to disrupt the function of a single gene, it can unintentionally target other genes, such as those located in the same operon as the deletion.
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| Autores principales: | , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
American Society for Microbiology
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/4ab3295f19b5446c8fc949767b9b3412 |
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| Sumario: | Single-gene deletion libraries have allowed genome-wide characterization of gene function and interactions. While each mutant intends to disrupt the function of a single gene, it can unintentionally target other genes, such as those located in the same operon as the deletion. |
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