Transcriptional and Post-Transcriptional Polar Effects in Bacterial Gene Deletion Libraries
Single-gene deletion libraries have allowed genome-wide characterization of gene function and interactions. While each mutant intends to disrupt the function of a single gene, it can unintentionally target other genes, such as those located in the same operon as the deletion.
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| Auteurs principaux: | , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2021
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/4ab3295f19b5446c8fc949767b9b3412 |
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| Résumé: | Single-gene deletion libraries have allowed genome-wide characterization of gene function and interactions. While each mutant intends to disrupt the function of a single gene, it can unintentionally target other genes, such as those located in the same operon as the deletion. |
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