A Novel Single-Cell RNA Sequencing Data Feature Extraction Method Based on Gene Function Analysis and Its Applications in Glioma Study

Critical in revealing cell heterogeneity and identifying new cell subtypes, cell clustering based on single-cell RNA sequencing (scRNA-seq) is challenging. Due to the high noise, sparsity, and poor annotation of scRNA-seq data, existing state-of-the-art cell clustering methods usually ignore gene fu...

Full description

Saved in:
Bibliographic Details
Main Authors: Jujuan Zhuang, Changjing Ren, Dan Ren, Yu’ang Li, Danyang Liu, Lingyu Cui, Geng Tian, Jiasheng Yang, Jingbo Liu
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
Online Access:https://doaj.org/article/4aff72a7f2aa4bb78055c14efbf49912
Tags: Add Tag
No Tags, Be the first to tag this record!