Alleviative Effect of Alpha-Lipoic Acid on Cognitive Impairment in High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats

Background: The intricate relationship between type 2 diabetes mellitus (T2DM) and Alzheimer’s disease (AD) suggests that insulin is involved in modulating AD-related proteins. Alpha-lipoic acid (ALA) can improve insulin resistance (IR) in diabetic rats. However, the role of ALA in alleviating the c...

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Main Authors: Chih-Yuan Ko, Jian-Hua Xu, Yangming Martin Lo, Rong-Syuan Tu, James Swi-Bea Wu, Wen-Chung Huang, Szu-Chuan Shen
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
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Online Access:https://doaj.org/article/4b35fe0043d342378a4257ead6f78e34
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