Uraemic toxins impair skeletal muscle regeneration by inhibiting myoblast proliferation, reducing myogenic differentiation, and promoting muscular fibrosis

Abstract Uraemic toxins increase in serum parallel to a decline in the glomerular filtration rate and the development of sarcopenia in patients with chronic kidney disease (CKD). This study analyses the role of uraemic toxins in sarcopenia at different stages of CKD, evaluating changes in the muscul...

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Autores principales: Elena Alcalde-Estévez, Patricia Sosa, Ana Asenjo-Bueno, Patricia Plaza, Gemma Olmos, Manuel Naves-Díaz, Diego Rodríguez-Puyol, Susana López-Ongil, María P. Ruiz-Torres
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4b37d63023314b8291db168f8e4ec209
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