Pharmacological and Epigenetic Regulators of NLRP3 Inflammasome Activation in Alzheimer’s Disease

Activation of the NLRP3 inflammasome complex results in the production of IL-18, Caspase-1 and IL-1β. These cytokines have a beneficial role in promoting inflammation, but an excessive activation of the inflammasome and the consequent constitutive inflammatory status is a negative factor in human pa...

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Détails bibliographiques
Auteurs principaux: Francesca La Rosa, Roberta Mancuso, Simone Agostini, Federica Piancone, Ivana Marventano, Marina Saresella, Ambra Hernis, Chiara Fenoglio, Daniela Galimberti, Elio Scarpini, Mario Clerici
Format: article
Langue:EN
Publié: MDPI AG 2021
Sujets:
D4T
R
Accès en ligne:https://doaj.org/article/4b94a6bf34874508a18178ee46cdecbb
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