Pharmacological and Epigenetic Regulators of NLRP3 Inflammasome Activation in Alzheimer’s Disease

Pharmacological and Epigenetic Regulators of NLRP3 Inflammasome Activation in Alzheimer’s Disease

Activation of the NLRP3 inflammasome complex results in the production of IL-18, Caspase-1 and IL-1β. These cytokines have a beneficial role in promoting inflammation, but an excessive activation of the inflammasome and the consequent constitutive inflammatory status is a negative factor in human pa...

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Autores principales: Francesca La Rosa, Roberta Mancuso, Simone Agostini, Federica Piancone, Ivana Marventano, Marina Saresella, Ambra Hernis, Chiara Fenoglio, Daniela Galimberti, Elio Scarpini, Mario Clerici
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
Alzheimer’s disease
D4T
miRNAs
NLRP3 inflammasome
Medicine
R
Pharmacy and materia medica
RS1-441
Acceso en línea:https://doaj.org/article/4b94a6bf34874508a18178ee46cdecbb
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https://doaj.org/article/4b94a6bf34874508a18178ee46cdecbb

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