BMSC-Derived Exosomes Ameliorate Osteoarthritis by Inhibiting Pyroptosis of Cartilage via Delivering miR-326 Targeting HDAC3 and STAT1//NF-κB p65 to Chondrocytes

Background. In the past decade, mesenchymal stem cells (MSCs) have been widely used for the treatment of osteoarthritis (OA), and noncoding RNAs in exosomes may play a major role. Aim. The present study is aimed at exploring the effect and mechanism of miR-326 in exosomes secreted by bone marrow mes...

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Auteurs principaux: Honggang Xu, Bin Xu
Format: article
Langue:EN
Publié: Hindawi Limited 2021
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Accès en ligne:https://doaj.org/article/4ba1463bcf1b43b793792160a149f541
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