Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease.
Severe acute respiratory syndrome coronavirus (SARS-CoV) encodes a papain-like protease (PLpro) with both deubiquitinating (DUB) and deISGylating activities that are proposed to counteract the post-translational modification of signaling molecules that activate the innate immune response. Here we ex...
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Autores principales: | , , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/4ba3475c68814eeabbd9182648e77f5b |
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