Increased mitochondrial protein import and cardiolipin remodelling upon early mtUPR.
Mitochondrial defects can cause a variety of human diseases and protective mechanisms exist to maintain mitochondrial functionality. Imbalances in mitochondrial proteostasis trigger a transcriptional program, termed mitochondrial unfolded protein response (mtUPR). However, the temporal sequence of e...
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Auteurs principaux: | , , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2021
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Accès en ligne: | https://doaj.org/article/4bc527a29d51462a9590e7b42257a8e8 |
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