Quantification of 1D, a novel derivative of curcumin with potential antitumor activity, in rat plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study in rats

Context: 1 D is a novel derivative of curcumin and shows very promising antitumor activities in various cancer cell lines. Objective: To characterize its preclinical pharmacokinetic profiles, a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the...

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Autores principales: Jialin Sun, Tao Jiang, Wen Xu, Zhangying Feng, Xianghua Quan, Ping Leng, Wei Sun, Jun Zhao, Fanbo Jing, Jing Li
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2019
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Acceso en línea:https://doaj.org/article/4bda032e6812435da947930f4b12d91c
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