Quantification of 1D, a novel derivative of curcumin with potential antitumor activity, in rat plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study in rats
Context: 1 D is a novel derivative of curcumin and shows very promising antitumor activities in various cancer cell lines. Objective: To characterize its preclinical pharmacokinetic profiles, a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for the...
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Auteurs principaux: | Jialin Sun, Tao Jiang, Wen Xu, Zhangying Feng, Xianghua Quan, Ping Leng, Wei Sun, Jun Zhao, Fanbo Jing, Jing Li |
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Format: | article |
Langue: | EN |
Publié: |
Taylor & Francis Group
2019
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Sujets: | |
Accès en ligne: | https://doaj.org/article/4bda032e6812435da947930f4b12d91c |
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