DOT1L inhibitors block abnormal self-renewal induced by cohesin loss
Abstract Acute myeloid leukemia (AML) is a high-risk malignancy characterized by a diverse spectrum of somatic genetic alterations. The mechanisms by which these mutations contribute to leukemia development and how this informs the use of targeted therapies is critical to improving outcomes for pati...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/4bea0347dc9d49beb5298d2cdd70741f |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|