ACLY Nuclear Translocation in Human Macrophages Drives Proinflammatory Gene Expression by NF-κB Acetylation

Macrophage stimulation by pathogen-associated molecular patterns (PAMPs) like lipopolysaccharide (LPS) or lipoteichoic acid (LTA) drives a proinflammatory phenotype and induces a metabolic reprogramming to sustain the cell’s function. Nevertheless, the relationship between metabolic shifts and gene...

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Autores principales:	Anna Santarsiero, Paolo Convertini, Simona Todisco, Ciro L. Pierri, Anna De Grassi, Niamh C. Williams, Dominga Iacobazzi, Giulio De Stefano, Luke A. J. O’Neill, Vittoria Infantino
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	ACLY inflammation macrophages nuclear translocation NF-κB p65 acetylation Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/4c0373f557ba404185f721458bb1f4e7
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ACLY Nuclear Translocation in Human Macrophages Drives Proinflammatory Gene Expression by NF-κB Acetylation

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