Synthesis of bridged tricyclo[5.2.1.01,5]decanes via nickel-catalyzed asymmetric domino cyclization of enynones

Tricyclo[5.2.1.01,5]decanes are often found in bioactive natural products; however, their synthesis poses significant challenges. Here, the authors report a nickel-catalyzed asymmetric domino cyclization of enynones, providing a rapid and modular synthesis of bridged tricyclo[5.2.1.01,5]decane skele...

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Autores principales: Jiachang Chen, Yiming Wang, Zhengtian Ding, Wangqing Kong
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/4c273223437a4e4692ee2bb0808ecbd9
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