Modeling and live imaging of mechanical instabilities in the zebrafish aorta during hematopoiesis

Abstract All blood cells originate from hematopoietic stem/progenitor cells (HSPCs). HSPCs are formed from endothelial cells (ECs) of the dorsal aorta (DA), via endothelial-to-hematopoietic transition (EHT). The zebrafish is a primary model organism to study the process in vivo. While the role of me...

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Autores principales: Dmitrii Chalin, Charlotte Bureau, Andrea Parmeggiani, Sergei Rochal, Karima Kissa, Ivan Golushko
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4c755f40f6754e448911725955fc6061
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