Modeling and live imaging of mechanical instabilities in the zebrafish aorta during hematopoiesis

Modeling and live imaging of mechanical instabilities in the zebrafish aorta during hematopoiesis

Abstract All blood cells originate from hematopoietic stem/progenitor cells (HSPCs). HSPCs are formed from endothelial cells (ECs) of the dorsal aorta (DA), via endothelial-to-hematopoietic transition (EHT). The zebrafish is a primary model organism to study the process in vivo. While the role of me...

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Autores principales: Dmitrii Chalin, Charlotte Bureau, Andrea Parmeggiani, Sergei Rochal, Karima Kissa, Ivan Golushko
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/4c755f40f6754e448911725955fc6061
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