A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study

A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study

Abstract Background A detailed understanding of the pathological processes involved in genetic frontotemporal dementia is critical in order to provide the patients with an optimal future treatment. Protein levels in CSF have the potential to reflect different pathophysiological processes in the brai...

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Main Authors: Sofia Bergström, Linn Öijerstedt, Julia Remnestål, Jennie Olofsson, Abbe Ullgren, Harro Seelaar, John C. van Swieten, Matthis Synofzik, Raquel Sanchez-Valle, Fermin Moreno, Elizabeth Finger, Mario Masellis, Carmela Tartaglia, Rik Vandenberghe, Robert Laforce, Daniela Galimberti, Barbara Borroni, Chris R. Butler, Alexander Gerhard, Simon Ducharme, Jonathan D. Rohrer, Anna Månberg, Caroline Graff, Peter Nilsson, on behalf of the Genetic Frontotemporal Dementia Initiative (GENFI)
Format: article
Language:EN
Published: BMC 2021
Subjects:
Cerebrospinal fluid
Neurofilament medium polypeptide (NEFM)
Neuronal pentraxin 2 (NPTX2)
Neurosecretory protein VGF (VGF)
Aquaporin 4 (AQP4)
LASSO
Neurology. Diseases of the nervous system
RC346-429
Geriatrics
RC952-954.6
Online Access:https://doaj.org/article/4c79ff7f1a074b35826ced4f2779339c
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https://doaj.org/article/4c79ff7f1a074b35826ced4f2779339c

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