Mitochondrial redox metabolism in trypanosomatids is independent of tryparedoxin activity.

Tryparedoxins (TXNs) are oxidoreductases unique to trypanosomatids (including Leishmania and Trypanosoma parasites) that transfer reducing equivalents from trypanothione, the major thiol in these organisms, to sulfur-dependent peroxidases and other dithiol proteins. The existence of a TXN within the...

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Autores principales: Helena Castro, Susana Romao, Sandra Carvalho, Filipa Teixeira, Carla Sousa, Ana M Tomás
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
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Acceso en línea:https://doaj.org/article/4c85c06044bc40729d2c1dcacd9b32da
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