Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins
Mutations in the human LMNA gene cause a collection of diseases called laminopathies, which includes muscular dystrophy and dilated cardiomyopathy. The LMNA gene encodes lamins, filamentous proteins that form a meshwork on the inner side of the nuclear envelope. How mutant lamins cause muscle diseas...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Elsevier
2021
|
| Subjects: | |
| Online Access: | https://doaj.org/article/4c9bdf11cf72460381870a3509fc100a |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|