Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins

Mutations in the human LMNA gene cause a collection of diseases called laminopathies, which includes muscular dystrophy and dilated cardiomyopathy. The LMNA gene encodes lamins, filamentous proteins that form a meshwork on the inner side of the nuclear envelope. How mutant lamins cause muscle diseas...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Gary S. Coombs, Jose L. Rios-Monterrosa, Shuping Lai, Qiang Dai, Ashley C. Goll, Margaret R. Ketterer, Maria F. Valdes, Nnamdi Uche, Ivor J. Benjamin, Lori L. Wallrath
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://doaj.org/article/4c9bdf11cf72460381870a3509fc100a
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!