Modulation of muscle redox and protein aggregation rescues lethality caused by mutant lamins
Mutations in the human LMNA gene cause a collection of diseases called laminopathies, which includes muscular dystrophy and dilated cardiomyopathy. The LMNA gene encodes lamins, filamentous proteins that form a meshwork on the inner side of the nuclear envelope. How mutant lamins cause muscle diseas...
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Autores principales: | , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Elsevier
2021
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Acceso en línea: | https://doaj.org/article/4c9bdf11cf72460381870a3509fc100a |
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