Structure and regulation of ZCCHC4 in m6A-methylation of 28S rRNA
The N6-methyladenosine (m6A) RNA modification is an evolutionarily conserved epitranscriptomic mechanism that impacts several cellular processes. Here the authors present a structure-function analysis of the ZCCHC4, 28S RNA-specific m6A methyltransferase, shedding light on its regulation and mechani...
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Autores principales: | Wendan Ren, Jiuwei Lu, Mengjiang Huang, Linfeng Gao, Dongxu Li, Gang Greg Wang, Jikui Song |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/4d0f1780040a49189c2e227179d984e8 |
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