Systemic inflammasome activation and pyroptosis associate with the progression of amnestic mild cognitive impairment and Alzheimer’s disease

Abstract Background Growing evidence indicates that inflammasome-mediated inflammation plays important roles in the pathophysiology of amnestic mild cognitive impairment (aMCI) and Alzheimer’s disease (AD). Pyroptosis induced by inflammasome, and Gasdermin D (GSDMD) is involved in several neurodegen...

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Autores principales: Wenjuan Rui, Hong Xiao, Yi Fan, Zhongxuan Ma, Ming Xiao, Sheng Li, Jingping Shi
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/4d208a1df015446b945d983e623a4b59
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