Chemotherapeutics and radiation stimulate MHC class I expression through elevated interferon-beta signaling in breast cancer cells.

Low doses of anticancer drugs have been shown to enhance antitumor immune response and increase the efficacy of immunotherapy. The molecular basis for such effects remains elusive, although selective depletion of T regulatory cells has been demonstrated. In the current studies, we demonstrate that t...

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Autores principales: Shan Wan, Sidney Pestka, Ronald G Jubin, Yi Lisa Lyu, Yu-Chen Tsai, Leroy F Liu
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/4d3adabd17e144ed8665bc735940c869
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