p53-Mediated Radiosensitization of <sup>177</sup>Lu-DOTATATE in Neuroblastoma Tumor Spheroids

p53 is involved in DNA damage response and is an exciting target for radiosensitization in cancer. Targeted radionuclide therapy against somatostatin receptors with <sup>177</sup>Lu-DOTATATE is currently being explored as a treatment for neuroblastoma. The aim of this study was to invest...

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Autores principales: Sara Lundsten, Hanna Berglund, Preeti Jha, Cecilia Krona, Mehran Hariri, Sven Nelander, David P. Lane, Marika Nestor
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
p53
Acceso en línea:https://doaj.org/article/4d7ad4c2ba884c0ea627c2e375ac1c7a
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