A novel in vitro method for detecting undifferentiated human pluripotent stem cells as impurities in cell therapy products using a highly efficient culture system.

Innovative applications of cell therapy products (CTPs) derived from human pluripotent stem cells (hPSCs) in regenerative medicine are currently being developed. The presence of residual undifferentiated hPSCs in CTPs is a quality concern associated with tumorigencity. However, no simple in vitro me...

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Bibliographic Details
Main Authors: Keiko Tano, Satoshi Yasuda, Takuya Kuroda, Hirohisa Saito, Akihiro Umezawa, Yoji Sato
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
R
Q
Online Access:https://doaj.org/article/4d820d1f61f44c70aa811667db34a3b0
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