A novel in vitro method for detecting undifferentiated human pluripotent stem cells as impurities in cell therapy products using a highly efficient culture system.

Innovative applications of cell therapy products (CTPs) derived from human pluripotent stem cells (hPSCs) in regenerative medicine are currently being developed. The presence of residual undifferentiated hPSCs in CTPs is a quality concern associated with tumorigencity. However, no simple in vitro me...

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Auteurs principaux: Keiko Tano, Satoshi Yasuda, Takuya Kuroda, Hirohisa Saito, Akihiro Umezawa, Yoji Sato
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/4d820d1f61f44c70aa811667db34a3b0
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