Light microscopy of proteins in their ultrastructural context

Imaging specific proteins in the ultrastructural context largely relies on correlative light/electron microscopy, but fluorophore incompatibility and registration issues limit its use. Here the authors develop an expansion microscopy method with pan-labeling of the proteome to obtain EM-equivalent l...

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Autores principales: Ons M’Saad, Joerg Bewersdorf
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/4d8ba5c29a00481891dbe1df9367f3e0
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