Genetic and pharmacological interrogation of cancer vulnerability using a multiplexed cell line screening platform

Xia et al. report the development and optimization of a high-throughput screening platform to systematically determine cancer cell sensitivity to pharmacological and genetic perturbations, BMS-PRISM, based on PRISM and high-throughput CRISPR/Cas9 loss-of-function screen technologies using cell line...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Yifeng Xia, Xiaodong Ji, In Sock Jang, Christine Surka, Christy Hsu, Kai Wang, Mark Rolfe, Neil Bence, Gang Lu
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Accès en ligne:https://doaj.org/article/4d8d29c70bdc4a77a7632fc27bcf2dfd
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!