Single-cell barcode analysis provides a rapid readout of cellular signaling pathways in clinical specimens

Diagnostic tests need optimization to avoid invasive and costly repeated biopsies. Here the authors present an antibody-DNA barcoding approach where harvested single cells can be re-stained through custom oligonucleotide-fluorophore conjugates, enabling multiplexed analysis of cancer pathways.

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Autores principales: Randy J. Giedt, Divya Pathania, Jonathan C. T. Carlson, Philip J. McFarland, Andres Fernandez del Castillo, Dejan Juric, Ralph Weissleder
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/4da7f9223b3c49949e8bbac7d3b4f4f6
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