A cell cycle kinase with tandem sensory PAS domains integrates cell fate cues

The membrane-bound kinase CckA controls the activity of the Caulobacter crescentusmaster regulator CtrA, which in turn coordinates asymmetric cell division. Here, the authors show that CckA contains two sensory domains that have distinct sensitivities to fluctuations in cyclic-di-GMP concentration a...

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Bibliographic Details
Main Authors: Thomas H. Mann, W. Seth Childers, Jimmy A. Blair, Michael R. Eckart, Lucy Shapiro
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/4dd75cb85cdd42dfa5b4a8cc1ccac2ef
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