A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth

Drosophila RNAi libraries are commonly used to perform large-scale functional genetics screens in vivo. Here the authors find that a subset of lines from the VDRC KK RNAi line cause false-positive enhancement of the Hippo pathway, and provide a strain that can test whether a genetic screen of intere...

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Bibliographic Details
Main Authors: Joseph H.A. Vissers, Samuel A. Manning, Aishwarya Kulkarni, Kieran F. Harvey
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/4def238a40cd4bc882d272cda03accde
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