Sara phosphorylation state controls the dispatch of endosomes from the central spindle during asymmetric division

Asymmetric segregation of cell fate determinants during cell division governs daughter cell fate. Here the authors show that Sara endosomes, known to regulate Notch signalling, are targeted to the mitotic spindle and once phosphorylated are asymmetrically dispatched into a daughter cell to determine...

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Autores principales: Sylvain Loubéry, Alicia Daeden, Carole Seum, Laurent Holtzer, Ana Moraleda, Nicolas Damond, Emmanuel Derivery, Thomas Schmidt, Marcos Gonzalez-Gaitan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/4e05d4052c0e463fa6494f9179a2fc71
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