Sara phosphorylation state controls the dispatch of endosomes from the central spindle during asymmetric division

Asymmetric segregation of cell fate determinants during cell division governs daughter cell fate. Here the authors show that Sara endosomes, known to regulate Notch signalling, are targeted to the mitotic spindle and once phosphorylated are asymmetrically dispatched into a daughter cell to determine...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Sylvain Loubéry, Alicia Daeden, Carole Seum, Laurent Holtzer, Ana Moraleda, Nicolas Damond, Emmanuel Derivery, Thomas Schmidt, Marcos Gonzalez-Gaitan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4e05d4052c0e463fa6494f9179a2fc71
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:4e05d4052c0e463fa6494f9179a2fc71
record_format	dspace
spelling	oai:doaj.org-article:4e05d4052c0e463fa6494f9179a2fc712021-12-02T17:01:24ZSara phosphorylation state controls the dispatch of endosomes from the central spindle during asymmetric division10.1038/ncomms152852041-1723https://doaj.org/article/4e05d4052c0e463fa6494f9179a2fc712017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15285https://doaj.org/toc/2041-1723Asymmetric segregation of cell fate determinants during cell division governs daughter cell fate. Here the authors show that Sara endosomes, known to regulate Notch signalling, are targeted to the mitotic spindle and once phosphorylated are asymmetrically dispatched into a daughter cell to determine cell fate.Sylvain LoubéryAlicia DaedenCarole SeumLaurent HoltzerAna MoraledaNicolas DamondEmmanuel DeriveryThomas SchmidtMarcos Gonzalez-GaitanNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sylvain Loubéry Alicia Daeden Carole Seum Laurent Holtzer Ana Moraleda Nicolas Damond Emmanuel Derivery Thomas Schmidt Marcos Gonzalez-Gaitan Sara phosphorylation state controls the dispatch of endosomes from the central spindle during asymmetric division
description	Asymmetric segregation of cell fate determinants during cell division governs daughter cell fate. Here the authors show that Sara endosomes, known to regulate Notch signalling, are targeted to the mitotic spindle and once phosphorylated are asymmetrically dispatched into a daughter cell to determine cell fate.
format	article
author	Sylvain Loubéry Alicia Daeden Carole Seum Laurent Holtzer Ana Moraleda Nicolas Damond Emmanuel Derivery Thomas Schmidt Marcos Gonzalez-Gaitan
author_facet	Sylvain Loubéry Alicia Daeden Carole Seum Laurent Holtzer Ana Moraleda Nicolas Damond Emmanuel Derivery Thomas Schmidt Marcos Gonzalez-Gaitan
author_sort	Sylvain Loubéry
title	Sara phosphorylation state controls the dispatch of endosomes from the central spindle during asymmetric division
title_short	Sara phosphorylation state controls the dispatch of endosomes from the central spindle during asymmetric division
title_full	Sara phosphorylation state controls the dispatch of endosomes from the central spindle during asymmetric division
title_fullStr	Sara phosphorylation state controls the dispatch of endosomes from the central spindle during asymmetric division
title_full_unstemmed	Sara phosphorylation state controls the dispatch of endosomes from the central spindle during asymmetric division
title_sort	sara phosphorylation state controls the dispatch of endosomes from the central spindle during asymmetric division
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/4e05d4052c0e463fa6494f9179a2fc71
work_keys_str_mv	AT sylvainloubery saraphosphorylationstatecontrolsthedispatchofendosomesfromthecentralspindleduringasymmetricdivision AT aliciadaeden saraphosphorylationstatecontrolsthedispatchofendosomesfromthecentralspindleduringasymmetricdivision AT caroleseum saraphosphorylationstatecontrolsthedispatchofendosomesfromthecentralspindleduringasymmetricdivision AT laurentholtzer saraphosphorylationstatecontrolsthedispatchofendosomesfromthecentralspindleduringasymmetricdivision AT anamoraleda saraphosphorylationstatecontrolsthedispatchofendosomesfromthecentralspindleduringasymmetricdivision AT nicolasdamond saraphosphorylationstatecontrolsthedispatchofendosomesfromthecentralspindleduringasymmetricdivision AT emmanuelderivery saraphosphorylationstatecontrolsthedispatchofendosomesfromthecentralspindleduringasymmetricdivision AT thomasschmidt saraphosphorylationstatecontrolsthedispatchofendosomesfromthecentralspindleduringasymmetricdivision AT marcosgonzalezgaitan saraphosphorylationstatecontrolsthedispatchofendosomesfromthecentralspindleduringasymmetricdivision
_version_	1718382145468104704

Sara phosphorylation state controls the dispatch of endosomes from the central spindle during asymmetric division

Ejemplares similares