Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma
Mucosal melanoma is a rare melanoma subtype that is poorly characterised. Here, the authors sequenced human, canine, and equine melanoma samples and performed a cross-species analysis, which revealed candidate driver genes, recurrent copy number alterations in regions syntenic between species, exten...
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Nature Portfolio
2019
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oai:doaj.org-article:4e13d3e9fe6547238116ebda7ade72442021-12-02T15:35:30ZCross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma10.1038/s41467-018-08081-12041-1723https://doaj.org/article/4e13d3e9fe6547238116ebda7ade72442019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-08081-1https://doaj.org/toc/2041-1723Mucosal melanoma is a rare melanoma subtype that is poorly characterised. Here, the authors sequenced human, canine, and equine melanoma samples and performed a cross-species analysis, which revealed candidate driver genes, recurrent copy number alterations in regions syntenic between species, extensive intra-tumour heterogeneity and potential germline predisposing allelesKim WongLouise van der WeydenCourtney R. SchottAlastair FooteFernando Constantino-CasasSionagh SmithJane M. DobsonElizabeth P. MurchisonHong WuIwei YehDouglas R. FullenNancy JosephBoris C. BastianRajiv M. PatelInigo MartincorenaCarla Daniela Robles-EspinozaVivek IyerMarieke L. KuijjerMark J. ArendsThomas BrennPaul W. HarmsGeoffrey A. WoodDavid J. AdamsNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
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DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Kim Wong Louise van der Weyden Courtney R. Schott Alastair Foote Fernando Constantino-Casas Sionagh Smith Jane M. Dobson Elizabeth P. Murchison Hong Wu Iwei Yeh Douglas R. Fullen Nancy Joseph Boris C. Bastian Rajiv M. Patel Inigo Martincorena Carla Daniela Robles-Espinoza Vivek Iyer Marieke L. Kuijjer Mark J. Arends Thomas Brenn Paul W. Harms Geoffrey A. Wood David J. Adams Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma |
| description |
Mucosal melanoma is a rare melanoma subtype that is poorly characterised. Here, the authors sequenced human, canine, and equine melanoma samples and performed a cross-species analysis, which revealed candidate driver genes, recurrent copy number alterations in regions syntenic between species, extensive intra-tumour heterogeneity and potential germline predisposing alleles |
| format |
article |
| author |
Kim Wong Louise van der Weyden Courtney R. Schott Alastair Foote Fernando Constantino-Casas Sionagh Smith Jane M. Dobson Elizabeth P. Murchison Hong Wu Iwei Yeh Douglas R. Fullen Nancy Joseph Boris C. Bastian Rajiv M. Patel Inigo Martincorena Carla Daniela Robles-Espinoza Vivek Iyer Marieke L. Kuijjer Mark J. Arends Thomas Brenn Paul W. Harms Geoffrey A. Wood David J. Adams |
| author_facet |
Kim Wong Louise van der Weyden Courtney R. Schott Alastair Foote Fernando Constantino-Casas Sionagh Smith Jane M. Dobson Elizabeth P. Murchison Hong Wu Iwei Yeh Douglas R. Fullen Nancy Joseph Boris C. Bastian Rajiv M. Patel Inigo Martincorena Carla Daniela Robles-Espinoza Vivek Iyer Marieke L. Kuijjer Mark J. Arends Thomas Brenn Paul W. Harms Geoffrey A. Wood David J. Adams |
| author_sort |
Kim Wong |
| title |
Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma |
| title_short |
Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma |
| title_full |
Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma |
| title_fullStr |
Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma |
| title_full_unstemmed |
Cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma |
| title_sort |
cross-species genomic landscape comparison of human mucosal melanoma with canine oral and equine melanoma |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/4e13d3e9fe6547238116ebda7ade7244 |
| work_keys_str_mv |
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