Rational design of complex phenotype via network models.

We demonstrate a modeling and computational framework that allows for rapid screening of thousands of potential network designs for particular dynamic behavior. To illustrate this capability we consider the problem of hysteresis, a prerequisite for construction of robust bistable switches and hence...

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Autores principales: Marcio Gameiro, Tomáš Gedeon, Shane Kepley, Konstantin Mischaikow
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
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Acceso en línea:https://doaj.org/article/4e3fa112aaf9476398ffc49fdda9e05f
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