Rational design of complex phenotype via network models.

We demonstrate a modeling and computational framework that allows for rapid screening of thousands of potential network designs for particular dynamic behavior. To illustrate this capability we consider the problem of hysteresis, a prerequisite for construction of robust bistable switches and hence...

Full description

Saved in:
Bibliographic Details
Main Authors: Marcio Gameiro, Tomáš Gedeon, Shane Kepley, Konstantin Mischaikow
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
Subjects:
Online Access:https://doaj.org/article/4e3fa112aaf9476398ffc49fdda9e05f
Tags: Add Tag
No Tags, Be the first to tag this record!