Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates.

Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates.

Genome-wide association (GWA) studies have identified a number of loci underlying variation in human serum uric acid (SUA) levels with the SLC2A9 gene having the largest effect identified so far. Gene-gene interactions (epistasis) are largely unexplored in these GWA studies. We performed a full pair...

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Auteurs principaux: Wenhua Wei, Gibran Hemani, Andrew A Hicks, Veronique Vitart, Claudia Cabrera-Cardenas, Pau Navarro, Jennifer Huffman, Caroline Hayward, Sara A Knott, Igor Rudan, Peter P Pramstaller, Sarah H Wild, James F Wilson, Harry Campbell, Malcolm G Dunlop, Nicholas Hastie, Alan F Wright, Chris S Haley
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2011
Sujets:
Medicine
R
Science
Q
Accès en ligne:https://doaj.org/article/4e6e1ec452014e6e9ec7fbcbfd1c12a9
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