An evolutionary perspective on epistasis and the missing heritability.

por Gibran Hemani, Sara Knott, Chris Haley
Publicado 2013

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

por Tom G. Richardson, Gibran Hemani, Tom R. Gaunt, Caroline L. Relton, George Davey Smith
Publicado 2020

Causal inference for heritable phenotypic risk factors using heterogeneous genetic instruments.

por Jingshu Wang, Qingyuan Zhao, Jack Bowden, Gibran Hemani, George Davey Smith, Dylan S Small, Nancy R Zhang
Publicado 2021

Assortative mating and within-spouse pair comparisons.

por Laurence J Howe, Thomas Battram, Tim T Morris, Fernando P Hartwig, Gibran Hemani, Neil M Davies, George Davey Smith
Publicado 2021

Assortative mating and within-spouse pair comparisons

por Laurence J. Howe, Thomas Battram, Tim T. Morris, Fernando P. Hartwig, Gibran Hemani, Neil M. Davies, George Davey Smith
Publicado 2021

Exploiting horizontal pleiotropy to search for causal pathways within a Mendelian randomization framework

por Yoonsu Cho, Philip C. Haycock, Eleanor Sanderson, Tom R. Gaunt, Jie Zheng, Andrew P. Morris, George Davey Smith, Gibran Hemani
Publicado 2020

Genetic evidence for assortative mating on alcohol consumption in the UK Biobank

por Laurence J. Howe, Daniel J. Lawson, Neil M. Davies, Beate St. Pourcain, Sarah J. Lewis, George Davey Smith, Gibran Hemani
Publicado 2019

Genetic Analyses of Common Infections in the Avon Longitudinal Study of Parents and Children Cohort

por Amanda H. W. Chong, Ruth E. Mitchell, Gibran Hemani, George Davey Smith, Robert H. Yolken, Rebecca C. Richmond, Lavinia Paternoster
Publicado 2021

High COVID-19 transmission potential associated with re-opening universities can be mitigated with layered interventions

por Ellen Brooks-Pollock, Hannah Christensen, Adam Trickey, Gibran Hemani, Emily Nixon, Amy C. Thomas, Katy Turner, Adam Finn, Matt Hickman, Caroline Relton, Leon Danon
Publicado 2021

Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

por Simon Haworth, Ruth Mitchell, Laura Corbin, Kaitlin H. Wade, Tom Dudding, Ashley Budu-Aggrey, David Carslake, Gibran Hemani, Lavinia Paternoster, George Davey Smith, Neil Davies, Daniel J. Lawson, Nicholas J. Timpson
Publicado 2019

Contacts and behaviours of university students during the COVID-19 pandemic at the start of the 2020/2021 academic year

por Emily Nixon, Adam Trickey, Hannah Christensen, Adam Finn, Amy Thomas, Caroline Relton, Clara Montgomery, Gibran Hemani, Jane Metz, Josephine G. Walker, Katy Turner, Rachel Kwiatkowska, Sarah Sauchelli, Leon Danon, Ellen Brooks-Pollock
Publicado 2021

Collider bias undermines our understanding of COVID-19 disease risk and severity

por Gareth J. Griffith, Tim T. Morris, Matthew J. Tudball, Annie Herbert, Giulia Mancano, Lindsey Pike, Gemma C. Sharp, Jonathan Sterne, Tom M. Palmer, George Davey Smith, Kate Tilling, Luisa Zuccolo, Neil M. Davies, Gibran Hemani
Publicado 2020

Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood

por Samuel W. Lukowski, Luke R. Lloyd-Jones, Alexander Holloway, Holger Kirsten, Gibran Hemani, Jian Yang, Kerrin Small, Jing Zhao, Andres Metspalu, Emmanouil T. Dermitzakis, Greg Gibson, Timothy D. Spector, Joachim Thiery, Markus Scholz, Grant W. Montgomery, Tonu Esko, Peter M. Visscher, Joseph E. Powell
Publicado 2017

Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates.

por Wenhua Wei, Gibran Hemani, Andrew A Hicks, Veronique Vitart, Claudia Cabrera-Cardenas, Pau Navarro, Jennifer Huffman, Caroline Hayward, Sara A Knott, Igor Rudan, Peter P Pramstaller, Sarah H Wild, James F Wilson, Harry Campbell, Malcolm G Dunlop, Nicholas Hastie, Alan F Wright, Chris S Haley
Publicado 2011

Author Correction: Bayesian reassessment of the epigenetic architecture of complex traits

por Daniel Trejo Banos, Daniel L. McCartney, Marion Patxot, Lucas Anchieri, Thomas Battram, Colette Christiansen, Ricardo Costeira, Rosie M. Walker, Stewart W. Morris, Archie Campbell, Qian Zhang, David J. Porteous, Allan F. McRae, Naomi R. Wray, Peter M. Visscher, Chris S. Haley, Kathryn L. Evans, Ian J. Deary, Andrew M. McIntosh, Gibran Hemani, Jordana T. Bell, Riccardo E. Marioni, Matthew R. Robinson
Publicado 2020

Bayesian reassessment of the epigenetic architecture of complex traits

por Daniel Trejo Banos, Daniel L. McCartney, Marion Patxot, Lucas Anchieri, Thomas Battram, Colette Christiansen, Ricardo Costeira, Rosie M. Walker, Stewart W. Morris, Archie Campbell, Qian Zhang, David J. Porteous, Allan F. McRae, Naomi R. Wray, Peter M. Visscher, Chris S. Haley, Kathryn L. Evans, Ian J. Deary, Andrew M. McIntosh, Gibran Hemani, Jordana T. Bell, Riccardo E. Marioni, Matthew R. Robinson
Publicado 2020

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

por Ben Brumpton, Eleanor Sanderson, Karl Heilbron, Fernando Pires Hartwig, Sean Harrison, Gunnhild Åberge Vie, Yoonsu Cho, Laura D. Howe, Amanda Hughes, Dorret I. Boomsma, Alexandra Havdahl, John Hopper, Michael Neale, Michel G. Nivard, Nancy L. Pedersen, Chandra A. Reynolds, Elliot M. Tucker-Drob, Andrew Grotzinger, Laurence Howe, Tim Morris, Shuai Li, The Within-family Consortium, The 23andMe Research Team, Adam Auton, Frank Windmeijer, Wei-Min Chen, Johan Håkon Bjørngaard, Kristian Hveem, Cristen Willer, David M. Evans, Jaakko Kaprio, George Davey Smith, Bjørn Olav Åsvold, Gibran Hemani, Neil M. Davies
Publicado 2020

Identical twins carry a persistent epigenetic signature of early genome programming

por Jenny van Dongen, Scott D. Gordon, Allan F. McRae, Veronika V. Odintsova, Hamdi Mbarek, Charles E. Breeze, Karen Sugden, Sara Lundgren, Juan E. Castillo-Fernandez, Eilis Hannon, Terrie E. Moffitt, Fiona A. Hagenbeek, Catharina E. M. van Beijsterveldt, Jouke Jan Hottenga, Pei-Chien Tsai, BIOS Consortium, Genetics of DNA Methylation Consortium, Josine L. Min, Gibran Hemani, Erik A. Ehli, Franziska Paul, Claudio D. Stern, Bastiaan T. Heijmans, P. Eline Slagboom, Lucia Daxinger, Silvère M. van der Maarel, Eco J. C. de Geus, Gonneke Willemsen, Grant W. Montgomery, Bruno Reversade, Miina Ollikainen, Jaakko Kaprio, Tim D. Spector, Jordana T. Bell, Jonathan Mill, Avshalom Caspi, Nicholas G. Martin, Dorret I. Boomsma
Publicado 2021

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

por Andrew P. Morris, Thu H. Le, Haojia Wu, Artur Akbarov, Peter J. van der Most, Gibran Hemani, George Davey Smith, Anubha Mahajan, Kyle J. Gaulton, Girish N. Nadkarni, Adan Valladares-Salgado, Niels Wacher-Rodarte, Josyf C. Mychaleckyj, Nicole D. Dueker, Xiuqing Guo, Yang Hai, Jeffrey Haessler, Yoichiro Kamatani, Adrienne M. Stilp, Gu Zhu, James P. Cook, Johan Ärnlöv, Susan H. Blanton, Martin H. de Borst, Erwin P. Bottinger, Thomas A. Buchanan, Sylvia Cechova, Fadi J. Charchar, Pei-Lun Chu, Jeffrey Damman, James Eales, Ali G. Gharavi, Vilmantas Giedraitis, Andrew C. Heath, Eli Ipp, Krzysztof Kiryluk, Holly J. Kramer, Michiaki Kubo, Anders Larsson, Cecilia M. Lindgren, Yingchang Lu, Pamela A. F. Madden, Grant W. Montgomery, George J. Papanicolaou, Leslie J. Raffel, Ralph L. Sacco, Elena Sanchez, Holger Stark, Johan Sundstrom, Kent D. Taylor, Anny H. Xiang, Aleksandra Zivkovic, Lars Lind, Erik Ingelsson, Nicholas G. Martin, John B. Whitfield, Jianwen Cai, Cathy C. Laurie, Yukinori Okada, Koichi Matsuda, Charles Kooperberg, Yii-Der Ida Chen, Tatjana Rundek, Stephen S. Rich, Ruth J. F. Loos, Esteban J. Parra, Miguel Cruz, Jerome I. Rotter, Harold Snieder, Maciej Tomaszewski, Benjamin D. Humphreys, Nora Franceschini
Publicado 2019