Hypoxia-inducible factor-2α is an essential catabolic regulator of inflammatory rheumatoid arthritis.

Rheumatoid arthritis (RA) is a systemic autoimmune disorder that manifests as chronic inflammation and joint tissue destruction. However, the etiology and pathogenesis of RA have not been fully elucidated. Here, we explored the role of the hypoxia-inducible factors (HIFs), HIF-1α (encoded by HIF1A)...

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Autores principales: Je-Hwang Ryu, Chang-Suk Chae, Ji-Sun Kwak, Hwanhee Oh, Youngnim Shin, Yun Hyun Huh, Choong-Gu Lee, Yong-Wook Park, Churl-Hong Chun, Young-Myeong Kim, Sin-Hyeog Im, Jang-Soo Chun
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/4e730e1e91e340d18d4720b3e8a542be
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