High Expression of <i>PPM1D</i> Induces Tumors Phenotypically Similar to <i>TP53</i> Loss-of-Function Mutations in Mice
<i>PPM1D</i> is a negative regulator of p53 and genomic aberrations resulting in increased activity of <i>PPM1D</i> have been observed in cancers of different origins, indicating that <i>PPM1D</i> has oncogenic properties. We established a transgenic mouse model o...
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/4e7642724943438284674a8797264157 |
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