Pan-cancer analysis of the effect of biopsy site on tumor mutational burden observations

Plain language summary The total number of mutations, or changes, found within the DNA of cancer cells in a tumor sample is known as the tumor mutational burden (TMB). TMB scores have been proposed to be a marker of how well a tumor might respond to immunotherapy, a type of treatment that triggers t...

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Autores principales: Simon Papillon-Cavanagh, Julia F. Hopkins, Shakti H. Ramkissoon, Lee A. Albacker, Alice M. Walsh
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/4e897cbc9b7e4b24833e722c9700416e
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